![]() Retina or vitreous, and in the absence of extracranial signs of Isolated to the optic nerve without infiltration of the brain, ![]() In immunocompetent patients, and less in those with AIDS ( 5). Treatment with radiotherapy and corticosteroids often only produceĪ partial response, and tumors recur in >90% of patients Generally ineffective due to the depth of the tumor. The causeįor the increase in incidence of this disease in the Primary central nervous system lymphoma (PCNSL) isĪn uncommon intracranial lesion that accounts for 10-fold from 2.5 cases toģ0 cases per 10 million population between 19 ( 2, 3). The present case emphasizes the importance of considering the diagnosis of lymphoma in this setting. Therefore, the present case of the lymphoma involving the optic nerve, optic chiasm and optic tract in an immunocompetent patient is unusual. To the best of our knowledge, PCNSL isolated to the optic chiasm has been reported only three times in immunocompetent patients. At a follow‑up examination 12 months after diagnosis, the patient demonstrated no evidence of recurrence. Following treatment with surgery and radiotherapy, the patient's symptoms went into remission. ![]() ![]() As no evidence of extracranial lymphoma was observed, the final diagnosis was primary central nervous system lymphoma (PCNSL). Postoperative examination indicated a diagnosis of diffuse malignant lymphoma type B. Brain imaging features were suggestive of malignant glioma of the anterior visual pathway. The current study reports the case of a 68‑year‑old, previously healthy female who presented with progressive visual impairment leading to blindness bilaterally. ![]()
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